Definition of immune staining of the entire retina of the retina

What is the function of the cone-rich rim of the retina?


Although there is good histological evidence for a rim of cones extending round the margin of the human retina at the ora serrata, the function of these cones is unknown, and indeed it is not known whether they are functional at all. Four possibilities are discussed here : (i) the cones of the ora serrata may alert us to sudden movements in the far peripheral field, (ii) their signal may be used in estimating optic flow during locomotion, (iii) they may integrate light scattered within the globe of the eye or passing through the sclera, for purposes of color constancy, or (iv) they may drive circadian rhythms. We report two experiments designed to detect psychophysical correlates of the cone rim. Under the conditions we have used, neither flicker detection nor color naming show, near the limit of vision, a discontinuity that would correspond to the cone-rich rim.


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Author information


  1. Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK

    J D Mollon & B C Regan

  2. Department of Visual Science, Institute of Ophthalmology, University College London, Bath Street, London, EC1V 9EL, UK

    J K Bowmaker

Corresponding author

Correspondence to J D Mollon.

additional information

This paper is dedicated to the memory of Professor H.J.A. Dartnall (1913-1998)

Supported by MRC grant 9712483

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Mollon, J., Regan, B. & Bowmaker, J. What is the function of the cone-rich rim of the retina ?. Eye12, 548-552 (1998).

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  • Color constancy
  • Cone
  • Cone streak
  • Flicker
  • Optic flow
  • Ora serrata
  • Peripheral retina

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